20 January 1862: Edwin Smith, an American antiquities dealer, lender, collector, and student of Egyptian writing resident at Luxor, bought the roll there from the dealer and consular agent Mustapha Agha Ayat. On 17 March Smith bought a composite modern forgery from the same seller; it incorporated fragments belonging to the first column of the authentic roll. No archaeological excavation records where the manuscript was found, and a possible Theban tomb context remains an inference (Science in Ancient Egypt).
1906: after Smith's death, his daughter Leonora Smith donated the manuscript to the New-York Historical Society. Naming the papyrus for its purchaser follows a modern collecting convention and leaves its Egyptian makers and users anonymous.
1930: after a decade of work, James Henry Breasted published photographs, hieroglyphic transcription, English translation, and extensive commentary, with medical notes by Arno B. Luckhardt. The edition made the complete text widely available and remains indispensable, but its language of “science,” “superstition,” and singular civilisational firsts also belongs to early twentieth-century historiography (Breasted 1930; Ritner 1993).
1938–1948: the papyrus was housed at the Brooklyn Museum before transfer to the New York Academy of Medicine in 1948. It remains there as inventory 217.
2005 and 2012: James P. Allen published a complete new translation with colour reproductions for a Metropolitan Museum of Art exhibition. Gonzalo M. Sanchez and Edmund S. Meltzer later produced a new transcription, translation, philological apparatus, and modern medical commentary. Their differences from Breasted show why an English rendering should be identified by edition rather than treated as the unmediated ancient text (Allen 2005; Sanchez and Meltzer 2012).